A. Sakamoto

Contribution of ictal-interictal SPECT and SISCOM to preoperative localization of the epileptogenic zone in frontal lobe epilepsy

Objective To describe the contributions of conventional single-photon emission computed tomography (SPECT) and subtraction ictal-interictal SPECT coregistered to magnetic resonance imaging (SISCOM) for the preoperative identification of the epileptogenic zone (EZ) in patients with frontal lobe epilepsy (FLE). Materials...

Pragmatic screening for autoimmune-associated epilepsy in drug-resistant epilepsy of unknown etiology in resource-limited settings: A hypothesis-generating study.

OBJECTIVE To evaluate the feasibility of investigating autoimmune etiology in adults with drug-resistant epilepsy (DRE) of unknown origin in resource-limited settings and to develop a pragmatic, hypothesis-generating screening approach to guide autoantibody testing. METHODS A prospective observational study including...

The Relationship Between Epilepsy and Neurocysticercosis: Evidence and Myths.

Longitudinal Bayesian analysis of lobe-specific cognitive outcomes after pediatric epilepsy surgery.

Epilepsy surgery preserved intellectual functioning, particularly in FL and PC procedures, however, persistent VCI decline in H and TL groups suggests effects on verbal abilities associated with temporal lobe involvement, and group-level trajectories rather than individual outcomes.

Beyond seizures: understanding adaptive functioning in drug-resistant epilepsy in patients undergoing palliative surgery

Palliative surgical procedures for pediatric DRE are safe and associated with seizure reduction, decreased medication burden, and gradual improvement in adaptive functioning and early surgical intervention may help minimize developmental decline and improve long-term adaptive outcomes.