Background Systemic lupus erythematosus (SLE) has a complex polygenic architecture, but translating genome-wide association signals into biologically interpretable candidates remains challenging. We applied an integrative post-GWAS framework to refine SLE-associated loci and prioritize candidate regulatory mechanisms....
V. Modhukur, Masuma Khatun, Naisarg Patel et al.· Journal of Translational Aut...· 0 citations
The mechanisms by which BPs interact with hormonal pathways are examined and their potential role in various hormone-related conditions, including benign gynecological diseases: endometriosis and polyendocrine metabolic ovarian syndrome/polycystic ovary syndrome and female gynecological cancers concerning breast, uteru...
Klaudia Żak, M. Bobiński, G. Moreno-Bueno et al.· Chemosphere· 0 citations
EMMA-STRAT provides an externally evaluated, research-grade computational framework for multi-omics molecular stratification of endometrial carcinoma and shows favorable discrimination and probability calibration relative to reference baselines, although calibration estimates for low-prevalence classes including POLE s...
Naisarg Patel, A. Salumets, V. Modhukur· BioData Mining· 1 citation
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