Open access
Oct 2026
Elucidating the Molecular Impact of DA29‐Induced ClpP Chemoactivation on Mitochondrial Function
ABSTRACT Cellular function relies on tightly regulated mitochondrial proteolysis, which controls organelle protein quality and specific mitochondrial functions, including gene expression and oxidative phosphorylation. In human mitochondria, one of the main proteolytic machineries is the soluble ClpXP complex, consistin...
Francesca Rizzo, Morena Miciaccia, Maria Grazia Perrone et al.
· The FASEB Journal · 0 citations