Author

A. Serrano-Pozo

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Open access Oct 2026

Associations between plasma biomarker levels and quantitative postmortem neuropathologic measures in Alzheimer's disease and related dementias

Abstract INTRODUCTION Validation of Alzheimer's disease blood‐based biomarkers (BBMs) has relied largely on amyloid beta (Aβ) and tau positron emission tomography (PET), with limited quantitative neuropathologic correlation studies. We examined associations between BBMs and quantitative postmortem neuropathology in 124...

Celia R. Bianco, Neus Rabaneda-Lombarte, Hadia A. Fatima et al. · Alzheimer's & Dementia · 0 citations

Open access Aug 2026

GFAP upregulation by astrocytes attenuates tau neurofibrillary tangle pathology in a mouse model of tauopathy

The upregulation of the intermediate filament glial fibrillary acidic protein (GFAP) by reactive astrocytes has been traditionally assigned structural functions such as the shaping of astrocyte morphology and the formation of the glial scar. However, in vitro studies have also implicated GFAP in chaperone-mediate...

C. Muñoz-Castro, Molly A. Healey, Ayush Noori et al. · Molecular Neurodegeneration · 0 citations