Author

A. Sewell

2 papers indexed here

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Open access Jun 2026

Optimized procurement of cancer-reactive T-cell receptors from clinical samples

Abstract T-cell receptors can sense cancer-associated changes in cellular proteins, lipids, metabolites, and stress pathways, enabling immune-mediated tumour elimination in some patients. These receptors underpin T-cell receptor-based immunotherapies, yet their isolation from clinical samples remains challenging due to...

Marine E. Caillaud, C. Rius, Théo Morin et al. · Immunotherapy Advances · 0 citations

Open access Sep 2026

VDJdb in 2026: boosting T-cell receptor recognition evidence using paratope embeddings and AI-based structure prediction.

We present a significant update to VDJdb, introducing substantial enhancements to both the data content and the technical infrastructure. The integration of steadily accumulating T-cell receptor (TCR):epitope recognition data, together with advances in high-throughput experimental techniques, has expanded the landscape...

D. Luppov, Anna E. Koneva, Dmitry V. Bagaev et al. · Nucleic Acids Research · 0 citations