Systemic lupus erythematosus (SLE) is a heterogeneous systemic autoimmune disease in which defective immune tolerance, nucleic-acid sensing, type I interferon activation, T- and B-cell dysregulation, immune-complex formation and tissue injury interact as a self-reinforcing network. MicroRNAs (miRNAs) are short non-codi...
A. Shlash, Kais Khudhair Al-hadrawi, J. M. Hussein· International Journal of Bio...· 0 citations
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease driven by a network of pro-inflammatory cytokines and epigenetic regulators that together sustain synovial inflammation and joint damage. Interleukin-21 (IL-21), produced mainly by T follicular helper and Th17 cells, has been implicated in the activa...
A. Shlash· Current Research in Health S...· 0 citations
Background: Rheumatoid arthritis (RA) is a chronic systemic autoimmune condition driven by synovial inflammation and arthritic destruction. MicroRNA-326 (miR-326) regulates Th17 cell differentiation, the major source of IL-17, a key pro-inflammatory cytokine in RA pathogenesis.
Objectives: The study aims to measure the...
A. Shlash, Kais Khudhair Al-hadrawi, Zahraa Basem· International Journal of Bio...· 0 citations
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