Review
Oct 2026
Advances in modeling chromosomal aberrations to recapitulate genomic rearrangements.
Chromosomal aberrations, including aneuploidies and structural rearrangements, are key drivers of cancer and numerous genetic disorders. Experimental modeling of these alterations is essential for understanding their role in disease initiation and progression. Historically, chromosome engineering relied on methods that...
Victoria Ginestet, Anna Schwager, Y. Vassetzky et al.
· Trends in Molecular Medicine · 0 citations