Aug 2026
Folic acid-functionalized PLGA-cystamine nanoparticles for glutathione-responsive capecitabine delivery in pancreatic cancer: in vitro and in vivo evaluation.
A glutathione-responsive nanocarrier system based on poly(lactic-co-glycolic acid) (PLGA) was designed, which introduced disulphide bonds that are stable in extracellular environments but cleaved in a reductive intracellular environment enriched with glutathione, demonstrating promising therapeutic efficacy.
Abhay Dev Tripathi, S. Katiyar, Vivek K. Chaturvedi et al.
· Journal of drug targeting (P... · 0 citations