Review
Open access
Jul 2026
Selective Inhibition of CK2: Emerging Strategies and Future Directions
This Perspective discusses three complementary strategies for selective CK2 inhibition: targeting the CK2α/β interface with small molecules, disrupting the same interface with conformationally constrained peptides, and exploiting the cryptic αD pocket for dual-site inhibitor design.
A. Sokhal, S. Krajcovicova, J. Iegre et al.
· Journal of Medicinal Chemist... · 0 citations