Open access
Sep 2026
Loss of FMRP leads to translationally relevant functional connectivity differences in a rat model of Fragile X Syndrome
It is found that Fmr1-/y rats displayed an age-dependent FC phenotype, with increased connectivity within the retrosplenial cortex (RSC) at 4 weeks but reduced connectivity within the RSC and distributed brain networks by adulthood compared with wild-type controls, which suggests FC abnormalities emerge over developmen...
Jing-Jing Ye, Joanna A. B. Surl, A. McKechanie et al.
· bioRxiv · 0 citations