Open access
Sep 2026
Sex-specific consequences of loss-of-imprinting of the maternally expressed gene Pleckstrin Homology-Like Domain Family A Member 2 (Phlda2) on placental development and fetal growth
A striking biological asymmetry is identified whereby female fetuses reduce their demands on the mother in response to Phlda2 loss-of-imprinting, whereas male fetuses do not, which is linked to sex-specific reproductive strategies in mammals in response to prenatal adversity.
A. Chibnall, D. Harrison, E. Lysikova et al.
· Biology of Sex Differences · 0 citations