Open access
Oct 2026
Perinatal nicotine exposure disrupts hematopoietic stem cell development and elevates influenza severity in adulthood.
Developmental exposures profoundly shape lifelong health by altering disease resilience later in life. One potential cause of increased disease susceptibility is an altered immune system, originating in epigenetically maladaptive hematopoietic stem cells (HSCs). Here, we establish perinatal nicotine exposure (PNE) as a...
M. Rommel, T. Cool, A. R. Y. Baena et al.
· Stem Cell Reports · 0 citations