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A. Takeno

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Open access Sep 2026

A multicenter phase II trial of ramucirumab plus irinotecan for early recurrence of gastric cancer during or after adjuvant chemotherapy with docetaxel plus S-1 therapy: the RAMIEL trial (OGSG1901).

BACKGROUND There is currently no established chemotherapy regimen for early recurrence of pathological stage III gastric cancer (GC) following adjuvant chemotherapy with docetaxel plus S-1 (DS) after D2 gastrectomy. We aimed to evaluate the efficacy and safety of ramucirumab plus irinotecan in patients with GC who expe...

Toshifumi Yamaguchi, R. Kawabata, Y. Akamaru et al. · 0 citations
Aug 2026

OA03-RF01.03. Non-Cisplatin-Based Preoperative Chemotherapy for Cisplatin-Unfit Esophageal Cancer: A Multicenter Retrospective Study in Japan

Esophageal Cancer: Adjuvant and Neo-Adjuvant Therapies Although cisplatin-based neoadjuvant chemotherapy is the standard for resectable esophageal squamous cell carcinoma in Japan, some patients are unfit due to age, renal, or cardiac dysfunction. No established treatment option exists for cisplatin-unfit...

Y. Ishizuka, Toru Kadono, Akitoshi Hakoda et al. · 0 citations
Sep 2026

Long-term nutritional outcomes after esophagectomy following induction chemotherapy versus chemoradiotherapy for T4b esophageal cancer.

Esophagectomy following induction chemoradiotherapy was associated with greater long-term weight loss and impaired nutritional recovery compared with surgery following chemotherapy alone, and these findings highlight the need for intensified nutritional surveillance and intervention in patients treated with preoperativ...

K. Sugimura, Koji Tanaka, T. Sugase et al. · 0 citations

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