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Open access Aug 2026

Efficient experimental characterization of the GPCRome via deep receptor scanning

A versatile “deep receptor scanning” platform is introduced that can be used to experimentally characterize 766 human GPCRs and 174 known GPCR splice variants in parallel and show that many highly-expressed receptors exhibit systematic differences in hydrophobicity and secondary structure.

A. Tedman, Muskan Goel, Sohan S. Shah et al. · 0 citations

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