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Author

A. Thitithanyanont

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2 papers indexed here

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Open access Oct 2026

ECDD-S16 exhibits broad-spectrum antiviral activity and inhibits an early, pH-dependent step of influenza virus entry.

Respiratory viral infections continue to pose a significant global health burden, highlighting the urgent need for broad-spectrum antiviral therapeutics. In this study, we identified ECDD-S16, an arylnaphthalene lignan derivative, as a potent broad-spectrum antiviral. ECDD-S16 exhibited dose-dependent antiviral activit...

Rattatammanoon Saengfak, Suwimon Manopwisedjaroen, Bumrung Munyoo et al. · 0 citations
Aug 2026

Galectin-3 exacerbates influenza a virus pathogenesis via dual mechanisms: Promoting hemagglutinin-dependent entry and driving nlrp3 inflammasome activation.

Gal3 is identified as a potent host factor that orchestrates excessive inflammation by simultaneously facilitating viral entry and driving the assembly of the NLRP3 inflammasome, highlighting the Gal3-NLRP3 axis as a promising therapeutic target to mitigate severe influenza-induced lung injury.

Zih-Syuan Yang, A. Thitithanyanont, Jason C. Huang et al. · 0 citations

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