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Open access Sep 2026

Children at familial high risk for schizophrenia or bipolar disorder show sex-specific differences in subcortical grey matter volumes

Background: Children of parents with schizophrenia (SZ) or bipolar disorder (BP) are at familial high risk (FHR) of developing severe mental illnesses. Based on findings in FHR populations and adults with SZ and BP, we hypothesized that children at FHR for schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP) would show...

M. M. Hansen, W. Baaré, E. Hernández-Torres et al. · 0 citations
Open access Aug 2026

Mental disorders in adolescents at familial high-risk of schizophrenia or bipolar disorder and population-based controls: An eight-year follow-up study, The Danish High Risk and Resilience Study, VIA 15

Background Children of parents with schizophrenia (SZ) or bipolar disorder (BP) show elevated rates of mental disorders. Longitudinal studies comparing offspring at familial risk with the background population are lacking. Method This study is an eight-year follow-up of the Danish High Risk and Resilience study. We exa...

D. H. B. Streymá, M. Gregersen, N. Weye et al. · 0 citations
Open access Sep 2026

Persistence of psychotic experiences and clinical outcomes in adolescents at familial high risk of schizophrenia or bipolar disorder: The Danish High Risk and Resilience Study

Objective: This study examined the prevalence of psychotic experiences (PE) and how early onset and persistence of PE contribute to risk and severity of mental disorders in adolescents at familial high-risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP) and adolescents from a population-based control group (PBC...

S. B. Rohd, A. Thorup, M. Wilms et al. · 0 citations

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