Author

A. Thureau

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Open access Nov 2026

A structural model for the autoinhibition of the γ-TuRC-activating CM1 domain.

Microtubule nucleation by γ-tubulin ring complexes (γ-TuRCs) must be spatiotemporally controlled to avoid major cell division errors. γ-TuRCs are activated by the centrosome-specific binding of a highly conserved centrosomin motif 1 (CM1) domain, but how binding is prevented in the cytosol remains unclear. We provide t...

Abir Elfarkouchi, A. Vitard, Léa Mammri et al. · Journal of Cell Biology · 0 citations

Open access Aug 2026

New design of a chimeric enzyme based on vanadium-dependent bromoperoxidase and glucose oxidase to highlight the microbicidal properties of the reaction products: HOBr and HOCl.

Vanadium-dependent haloperoxidases are enzymes found in bacteria, fungi and red or brown macroalgae. They are used as a defense system for the latter by producing bromoform. The intermediate product, HOBr or HOCl, is also a microbicidal compound that can be exploited in many domains as medical tools or disinfectant spr...

V. Amalric, S. Gounel, A. Thureau et al. · Journal of Biotechnology · 0 citations