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Author

A. Thurm

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Open access Sep 2026

Feasibility of Functional Near-Infrared Spectroscopy in Assessing Prefrontal Cortical Activation During Behaviour Inhibition in Williams Syndrome.

BACKGROUND Williams syndrome (WS) is a genetic condition associated with neurodevelopmental disorders including intellectual disability and executive functioning (EF) deficits. Although neuroimaging methods may clarify the neural basis of these impairments, participant burden and frequent exclusion of individuals with...

E. Condy, M. Sargeant, A. Thurm et al. · 0 citations
Open access Aug 2026

Preserved social development but impaired executive function in a Shank3-deficient rat model of Phelan-McDermid syndrome

Rats with complete or partial Shank3 deficiency produce a selective behavioral profile in which high-order cognitive dysfunction is more pronounced than deficits in basic sensorimotor or select social behaviors, and these findings highlight executive dysfunction as a key consequence of the loss of Shank3.

Anna C. Pearson, T. Drazan, Sean P. Bradley et al. · 0 citations

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