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A. Torsvik

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Open access Jul 2026

Integrative multiomics profiling of cortical brain organoids reveals a druggable alternative splicing program in schizophrenia

This work derived cortical brain organoids from a large cohort of schizophrenia (SCZ) patients and healthy controls and employed a comprehensive multiomics strategy to dissect the cellular mechanisms of long-term CLZ exposure, uncovered a SCZ-specific and metabolism-independent alternative splicing program that was ame...

I. Akkouh, Jordi Requena Osete, A. Szabo et al. · 0 citations

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