Open access
Oct 2026
Design and Evaluation of Novel Peptides Targeting Protein Disulfide Isomerase as Antiplatelet Agents
Extracellular protein disulfide isomerase (PDI) is a critical mediator of thrombus formation and a promising target for novel antithrombotic therapies aiming to overcome the bleeding risks associated with current antiplatelet agents. This study aimed to design and evaluate novel, targeted peptide-based PDI inhibitors w...
Francisca Rodríguez-Cabello, Diego Méndez, Eugenia Ulzurrun et al.
· Molecules · 0 citations