Mitochondria are attractive targets for anticancer therapy because of their central role in cellular metabolism and apoptosis. Here, we report a series of hydroxypropyl-functionalized imidazolium surfactants (HPIm-n, n = 12, 14, 16, and 18) and their use as non-covalent modifiers of liposomal nanocarriers. The surfacta...
D. Kuznetsova, D. Kuznetsov, E. Vasilieva et al.· Colloids and Surfaces B: Bio...· 0 citations
A series of triphenylphosphonium (TPP) conjugates of 1,2,3-triazolyl analogues of pyrimidine nucleosides was synthesized. In these compounds a TPP cation was attached via a decamethylene linker to the atom N-3 of the nucleic base (uracil, thymine) or its analog (6-methyluracil), and the N-acetyl-β-D-glucosamine residue...
Leysan R. Safargalieva, B. Garifullin, R. F. Aznagulov et al.· Nucleosides, Nucleotides & N...· 0 citations
Pyrrolidinium amphiphiles bearing a hydroxyethyl fragment [MPSn(OH), where n = 12, 14, 16, 18] were used as a modifier for the preparation of cationic hybrid liposomes based on phosphatidylcholine and cholesterol. The composition of the nanocarriers was optimized by varying the surfactant alkyl chain length and the lip...
Roman A. Babkin, E. Vasilieva, L. Vasileva et al.· Russian journal of general c...· 0 citations
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