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A. W. Khan

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Review Open access Sep 2026

Methylglyoxal as a Potential Mediator of Metabolic Memory in Diabetes-Related Complications: From Oxidative Stress to Macromolecular Glycation and Epigenetic Remodeling

Diabetes-related complications often continue to progress despite improved glycemic control, a phenomenon known as metabolic memory. Increasing evidence suggests that methylglyoxal (MGO), a highly reactive dicarbonyl generated during glycolysis, may be an important mediator of this process. Hyperglycemia-induced oxidat...

Maya A. K. Stelzer, A. W. Khan, J. Kroon et al. · 0 citations

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