Immunophenotypic insights into diabetes heterogeneity: The role of CD25-expressing T cells in Ghanaian type 1 diabetes cohorts
Type 1 diabetes (T1D) in sub-Saharan Africa exhibits heterogeneity, characterised by alternative phenotypes that retain C-peptide levels. The T-cell pathology linked to these atypical phenotypes remains largely unexplored. CD25, the interleukin-2 receptor alpha chain, and IL2RA genetic variants are key T-cell factors i...