Review
Open access
Jul 2026
Patient‐Derived Organoid‐Based CRISPR Screens in Cancer Research: Applications, Advances, and Challenges
It is argued that the major value of organoid‐based CRISPR screening lies in its ability to identify functionally actionable cancer vulnerabilities in a patient‐contextualized model, while also introducing methodological challenges that must be addressed for robust clinical translation.
J. du Plessis, Aadilah Omar
· Cancer Medicine · 0 citations