A microfluidic and mechanistic modeling approach to enhance oral bioavailability of cannabidiol via poloxamer-coated camel milk exosomes.
Cannabidiol (CBD) has significant therapeutic potential, but its oral delivery remains limited by poor aqueous solubility, variable intestinal absorption, and extensive first-pass metabolism. This study evaluated Poloxamer 407-coated camel milk-derived exosomes (CBD-CMDE-P407) as an oral nanocarrier system for improvin...