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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Aaron Cho

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Open access Sep 2026

Allosteric pathways govern Gα protein coupling selectivity at promiscuous GPCRs

It is suggested that Gα protein selectivity is an allosterically encoded property of GPCRs and provide a conceptual framework for designing ligands and receptors with tailored Gα protein-biased signaling.

Tegvir S. Boora, Han-Yu Chen, Aaron Cho et al. · 0 citations

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