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Author

Aastha Pal

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Open access Aug 2026

A Mammalian High-Throughput Screen for AI-Designed Peptide-Guided Protein Degraders

Targeted protein degradation (TPD) offers a route to eliminate disease-driving proteins that remain inaccessible to conventional inhibitors. However, degrader discovery remains low-throughput, labor-intensive, and dependent on randomized libraries or non-human display systems, limiting functional selection in mammalian...

Lin Zhao, Anuoluwapo A. Mattix, Aastha Pal et al. · 0 citations

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