Abdalrahman Khalifa

Novel pyrimidine-2,4-thiazolidinedione hybrids as dual antimicrobial and anti-virulent agents: synthesis, DNA gyrase B inhibition, and computational investigations.

Globally, antimicrobial resistance (AMR) poses a serious threat to human health and is often associated with poor treatment outcomes. There is an urgent need for effective therapeutic options to address this escalating issue. This study deals with the design and synthesis of new analogs based on the hybridization of th...