Abdessalem Hammed

Targeting capillary leak in experimental sepsis and endotoxemia: a systematic review of therapeutic agents, methods and models in animal studies

Sepsis-induced capillary leak is a major contributor to circulatory dysfunction and tissue edema, yet remains therapeutically unaddressed: numerous interventions showing promise in preclinical models have failed to demonstrate clinical efficacy. This systematic review aimed to characterise preclinical studies evaluatin...