GENETIC CHARACTERIZATION OF PLASMID-MEDIATED COLISTIN RESISTANCE GENES IN MULTIDRUG RESISTANT KLEBSIELLA PNEUMONIAE
Background: Antimicrobial resistance in Klebsiella pneumoniae is a growing global health concern, with rising multidrug- and carbapenem-resistant strains narrowing treatment options. Colistin remains a last-resort agent, but plasmid-mediated mobile colistin resistance (mcr) genes threaten its efficacy through horizonta...