Osteoarthritis (OA) is a leading cause of chronic pain and disability. Its increasing global prevalence and substantial socioeconomic burden highlights need for safer and more effective therapeutic strategies. Current pharmacological treatments provide symptomatic relief; however, are limited by gastrointestinal, cardi...
Ahmed I. Anwar, T. Apgar, Abdul-rahman A. Hegazi et al.· Pain and Therapy· 0 citations
Chronic musculoskeletal pain remains a leading cause of disability worldwide, driven by progressive degeneration of cartilage, bone, tendon, intervertebral discs, and peripheral nerves. Conventional interventional approaches primarily address symptoms without restoring structural integrity or tissue homeostasis. Regene...
Hamsa Priya Bhuchakra, Ahmed I. Anwar, Abdul-rahman A. Hegazi et al.· Biophysica· 0 citations
Neurodegenerative diseases are targets for pridopidine therapy, which aims to improve quality of life through neuroprotective mechanisms that involve sigma-1 receptor (S1R) activation. Neurodegenerative motor and cognitive diseases are influenced by dopamine imbalance, where disruptions in pathways contribute to states...
Ahmed I. Anwar, Abdul-Rahman A. Hegazi, Hamsa Priya Bhuchakra et al.· Neurology International· 0 citations
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