Intravitreal curcumin-loaded nanostructured lipid carriers for the management of post-traumatic proliferative vitreoretinopathy: optimization, in vitro characterization, and in vivo animal study.
Proliferative vitreoretinopathy (PVR) is a pathological vision-threatening complication that develops after a penetrating ocular trauma, retinal detachment and/or retinal reattachment surgery. After retinal break, epidermal growth factor (EGF) mediates the proliferation and dedifferentiation of retinal pigment epitheli...