Author

Abhijit Behera

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Review Open access Sep 2026

De Novo Discovery of Bioactive Cyclic Peptides via Cellular Selection of Genetically Encoded Libraries

Cellular selection has emerged as a powerful approach for high throughput de novo discovery of bioactive cyclic peptides (CPs). This strategy coexpresses genetically encoded CP libraries with the target of interest in cells and uses customizable selection systems to link desired CP activities to a selectable phenotype...

Lin-Wei Yang, Abhijit Behera, Hannah J. Meyers et al. · ChemBioChem · 0 citations

Open access Sep 2026

Phage-assisted continuous evolution of enzymes for noncanonical tyrosine biosynthesis

It is shown that phage-assisted evolution can be used to rapidly optimize enzymes for the synthesis of noncanonical tyrosine derivatives in Escherichia coli and this platform provides a powerful approach for the rapid engineering of ncAA synthases amenable to use in cells.

James S. Andon, Abhijit Behera, Debashrito Deb et al. · Proceedings of the National... · 0 citations