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Abhijit Mohapatra

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2026

Identification of 2,4-dihydroxy-azaflavanone as an allosteric activator of SIRT1 and its potential role in cellular models of Parkinson's disease.

This chapter outlines a detailed, multi-layered methodological framework for assessing the allosteric activation of SIRT1 by 2,4-dihydroxy-azaflavanone and its downstream effects in a cellular models of PD.

Chitrakshi Pant, Vidya Jyothi Alli, Genji Sukumar et al. · 0 citations
Open access Jul 2026

A lipid acyl code-based Dip2-Pkc1 signalling axis maintains mitochondrial integrity in eukaryotes

This study uncovers a novel, Dip2-mediated, unconventional Pkc1 signalling axis for maintaining mitochondrial homeostasis under nutrient transition and highlights how distinct lipid fingerprints enable precise control over organellar homeostasis.

Santhosh Kumar, Sakshi Shambhavi, Azeen Zehra et al. · 0 citations

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