Abhijit S. Deore

Coumarin-triazine hybrid pharmacophores as new EGFR inhibitors against cancer cell lines: Synthesis, computational studies, and in vitro cytotoxic evaluation

A new line of triazine-benzopyran hybrid compounds, 1,3,5-triazin-2-yl) oxy)-4-methyl-2H- chromen-2- ones, has been developed, synthesized, and physiologically explored as epidermal growth factor receptor (EGFR) inhibitors for cancer treatment. The work used pharmacophore hybridization to increase receptor affinity and...