Abhishek De

In-depth comparison of dengue virus laboratory strains and clinical isolates in terms of growth properties and NS1 production and detection in hepatic and non-hepatic cell lines.

Dengue virus (DV) is a major arboviral pathogen, with the liver being a primary target organ. The viral non-structural protein-1 (NS1) plays important roles in replication, autoimmunity, and pathogenesis, but strain-specific differences in NS1 secretion and cell responses remain incompletely understood. In this study,...