Gastrointestinal (GI) cancers, including colorectal, gastric, pancreatic, hepatocellular, and esophageal malignancies, remain a leading cause of cancer-related mortality worldwide. Emerging evidence identifies the gut microbiome as a critical regulator of GI carcinogenesis, influencing tumor initiation, immune evasion,...
Mathab Adam, Adwaith Venugopal, Amir Almohana et al.· Cell Cycle· 0 citations
NEDDylation marks a degradation-resistant pool of eIF3g/eIF3i that is competent for SG localization, linking the NEDD8 pathway to initiation-factor proteostasis and condensate partitioning, and potentially making these factors available for translation reinitiation during stress recovery.
A. Jayabalan, Ramesh Mariappan, Abirami Rajendiran et al.· bioRxiv· 0 citations
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