Abraham Méndez-Fernández

Mitochondrial respiratory complexes, excitation-contraction coupling and mTOR signaling transcriptional programs are dysregulated in cardiometabolic HFpEF

Heart failure is a leading cause of death and disability worldwide. Nearly, half of the cases correspond to HF with preserved ejection fraction (HFpEF), which is predicted to become the most prevalent form of HF in the forthcoming years. In this study, we performed a bulk RNA-seq assay to study the transcriptomic profi...