Diethyl phthalate exposure promotes colon cancer progression through ALDOC mediated proliferation, epithelial-mesenchymal transition, and ferroptosis resistance.
Colon cancer is a global health threat characterized by marked heterogeneity and therapeutic resistance. Although environmental pollutants may contribute to tumor progression, the role of diethyl phthalate (DEP), a widely used plasticizer and endocrine disruptor, remains unclear. By integrating clinical cohort data, bi...