Single-Cell Analysis of Human SVF Reveals Early Transcriptional and Communication Shifts During ASC Culture Expansion
BACKGROUND: Adipose-derived stem cells (ASCs) are known in regenerative medicine due to their multi-potency, immunomodulatory function, and facile isolation from the stromal vascular fraction (SVF). However, the specific SVF cell types that contribute to therapeutic efficacy and the mechanisms by which either fresh SVF...