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Author

Adam Murray

2 papers indexed here

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Open access Sep 2026

Structured and target-specific development of cortico-cortical connectivity in the mouse visual cortex.

The mammalian cortex exhibits highly stereotyped long-range connectivity, yet the developmental principles specifying precise cortico-cortical projection patterns remain poorly defined. Two dominant models propose that target specificity arises either from exuberant outgrowth followed by pruning, or through initially d...

Matthew W. Jacobs, John M. Ratliff, Alec L. R. Soronow et al. · 0 citations
Open access Jul 2026

Massively Parallel, Single-Molecule Assessment of Synthetic Fidelity and Drug-Like Properties in a DNA-Encoded Library.

DNA-encoded libraries (DELs) are powerful drug discovery tools, enabling rapid hit generation against immobilized protein targets. However, translating these hits is often hampered by synthetic inefficiency and, for libraries of "beyond-Rule-of-5" compounds such as macrocyclic peptides, by enrichment of poorly cell-per...

Grant Koch, M. F. Lawler, Adam Murray et al. · 0 citations

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