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Author

Adem Atacak

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Open access Sep 2026

Hepatoprotective effect of zinc in aged type 2 diabetic rats

Aims: This study aimed to evaluate the effects of intraperitoneal zinc (Zn) supplementation on hepatic structural alterations, enzymatic antioxidant capacity, and metabolic regulation in an aged diabetic rat model.Methods: Female rats aged 18 months type 2 diabetes mellitus (T2DM) was induced using a high-fat diet (HFD...

Ö. Ünal, Adem Atacak, Elif Gülbahçe Mutlu · 0 citations
Open access Aug 2026

Neuroprotective Effects of Zinc Sulfate Against Type 2 Diabetes-Induced Encephalopathy in Aged Rats

ZnSO4 supplementation provides potent, multifaceted neuroprotection against T2DM-associated neurodegeneration by regulating systemic dyslipidemia, restoring redox homeostasis, activating the SIRT-1/BDNF anti-apoptotic pathway, and preserving structural integrity.

O. Unal, N. Akgun-Unal, E. S. Tiryaki et al. · 0 citations

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