Effects of paraprobiotic Lactobacillus acidophilus LA-5 on PANoptosis, oxidative stress and inflammation in acetic acid-induced ulcerative colitis.
BACKGROUND Ulcerative colitis (UC) is a relapsing inflammatory bowel disease characterised by oxidative stress, inflammation and regulated cell death of the colonic mucosa. Because live probiotics may cause bacteraemia and sepsis in immunocompromised hosts, non-viable (paraprobiotic) alternatives have attracted interes...