Author

Adriana Kahn

2 papers indexed here

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Open access Oct 2026

TP53 Genomic Alterations Including Targetable Y220C Mutation in Advanced Breast Cancer

TP53 Y220C is a rare genomic alteration (GA) with emerging targeted therapies. However, its prevalence in breast cancer remains undefined. We evaluated the prevalence of the Y220C alteration and association with other GAs. A total of 23,760 patients with advanced breast cancer were analyzed by hybrid ca...

N. Casasanta, Adriana M. Kahn, N. Fischbach et al. · JCO Oncology Advances · 0 citations

Review Open access Aug 2026

Beyond a single disease: review of rare histological subtypes of triple-negative breast cancer with implications for prognosis and treatment

Triple-negative breast cancer (TNBC) is commonly approached as a single clinical entity despite marked biological heterogeneity. A subset of cases corresponds to rare histologic subtypes that display distinct molecular drivers, immune microenvironments, and clinical behavior. In this Review, we summarize the clinicop...

M. Gouveia, R. Bonadio, R. Barroso-Sousa et al. · npj Breast Cancer · 0 citations