Aeshah A. Awaji

Immune cell-derived exosomes in the tumor microenvironment: mechanisms of immune evasion and emerging therapeutic strategies in cancer immunotherapy

Tumor-released exosomes have emerged from the shadows of “cellular dust” to be recognized as pivotal mediators of intercellular communication within the tumor microenvironment (TME). These nano-sized vesicles (30–150 nm) carry a complex cargo of proteins, lipids, and nucleic acids that profoundly reshape anti-tumor imm...