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Agnieszka B. Olejniczak

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Open access Aug 2026

The discovery of potent and selective N6-modified adenosine derivatives as effective chemotherapeutic agents to overcome p53-dependent drug resistance in cancer and HPIV-3/AdV5 respiratory tract infections.

N6-modified adenosines are identified as a promising class of compounds for developing anticancer agents with p53-independent activity and reveal several derivatives as attractive scaffolds for further optimization toward antiviral agents targeting respiratory viruses.

Elżbieta Speina, Katherine Burchiellaro, Marta Denel-Bobrowska et al. · 0 citations
Open access Aug 2026

Carboranes as Modulators of Biologically Active Compounds: Case Studies of DNA-Intercalating Agents, Penicillin G and Isoniazid.

This chapter summarizes recent advances in the design of carborane-containing derivatives of biologically active scaffolds, including 1,8-naphthalimides, acridines, penicillin G, and isoniazid derivatives, and represents promising tools for the development of novel anticancer and antimicrobial agents.

Agnieszka B. Olejniczak · 0 citations

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