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Author

Agustina Bruno-Vignolo

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Jul 2026

Huntingtin is a cell-autonomous regulator of neuropeptide trafficking and clock output

Through targeted genetic knock-down, huntingtin is identified as a cell-autonomous regulator of neuropeptide trafficking, neuronal excitability and circadian output and carries direct relevance for HD therapeutic strategies, particularly those involving huntingtin-lowering approaches.

Agustina Bruno-Vignolo, Cayetana Arnaiz, Florencia Fernández-Chiappe et al. · 0 citations