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Integrated in silico identification of fungal-derived dual-target inhibitors for anti- schistosomal drug discovery
Praziquantel, which has limited efficacy against young parasites and reduces susceptibility, is the principal therapy for schistosomiasis, a neglected tropical illness. This work identified fungal- derived compounds with potential dual inhibitory action against Schistosoma mansoni DHODH and cathepsin B1 using an integr...