Ahmed A. El-Sayed

Novel bis(benzylidene)-6-methyl-2-thiouracil derivatives: design, synthesis, and molecular docking as potential antimicrobial agents against multidrug-resistant pathogenic bacteria

The synthesized compounds exhibited favorable drug-likeness, satisfactory solubility, and minimal anticipated toxicity, as per an in silico ADMET study, indicating that compound 2e and other bis(benzylidene)-thiouracil derivatives are viable candidates for the development of new antimicrobial drugs targeting resistant...