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Author

Ahmed A. Sobhy

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Sep 2026

Novel pyrimidine-based N-Acylhydrazones as dual AChE inhibitors and antioxidants targeting Alzheimer's disease.

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by cholinergic dysfunction and oxidative stress, making the development of multi-target-directed ligands (MTDLs) an attractive therapeutic strategy. Herein, we designed and synthesized a novel series of pyrimidinone-based acyl hydrazo...

M. N. Abd Al Moaty, A. Moustafa, Alaa S. Hegazy et al. · 0 citations

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